Our Team

Principal Investigator

Dr. Erin C. Dunn

Dr. Erin C. Dunn is a social and psychiatric epidemiologist with expertise in genetics and epigenetics. Her research laboratory uses interdisciplinary approaches to better understand the social and biological factors that influence the etiology of depression among women, children, and adolescents. The goal of her work is to identify the causal mechanisms underlying risk for depression, translate that knowledge to population-based strategies for prevention, and target those strategies to “sensitive periods” in development. Sensitive periods are high-risk/high-reward stages in the course of the lifespan when experience, whether exposure to adversity on the one hand or health-promoting interventions on the other, can have lasting impacts on brain health. Through her efforts to determine when these sensitive periods occur, her goal is to design interventions that not only promote brain health across the lifespan, but are also uniquely timed to minimize the consequences of stress exposure, prevent depression before it onsets, and make the most efficient use of limited public health dollars. Dr. Dunn is currently an Associate Professor of Psychiatry at Harvard Medical School and an Associate Investigator at Massachusetts General Hospital (MGH) and is affiliated with the Broad Institute of Harvard and MIT, the Center on the Developing Child at Harvard, and the Henry and Allison McCance Center for Brain Health at MGH. She has led several genetic association studies and gene-environment interaction studies that were the first of their kind, including publishing some of the first genome-wide association studies of depression risk in non-European ancestry populations and the first genome-wide environment interaction study of depression. Her research has been recognized by the Anxiety and Depression Association of America through the Donald F. Klein Early Career Investigator Award and the Brain & Behavior Research Foundation through the Gerald R. Klerman Award, Honorable Mention. She is a 2017 recipient of a National Institute of Mental Health-funded Biobehavioral Research Award for Innovative New Scientists (BRAINS). In 2018, she was awarded a Rising Star award from One Mind. In 2020, Dr. Dunn received a research mentoring award from the Department of Psychiatry at MGH. Dr. Dunn is a first-generation college student. Given her research on baby teeth, she is also known as the Science Tooth Fairy.


Program Director

Alison is Program Director of the Dunn Lab. She has over two decades experience as a research and program administrator, including with the World Mental Health Survey Initiative at Harvard Medical School, the Mass General site of the Mass General Brigham Biobank, and most recently as a Program Director in the Mass General Research Institute. She holds a Masters degree in Management, focused on research administration. In the Dunn Lab, Alison provides operational and administrative oversight of all Initiatives.

Alison Hoffnagle


Research Fellows

  • Simone Lemmers

    Simone Lemmers, Ph.D., is a biological anthropologist joining the Dunn Laboratory as a research fellow with expertise in dental and bone histology. Simone is broadly interested in how we can use hard tissues to answer questions on life history, growth, development and responses to physiological stress, in both modern and fossilised tissues. She completed her PhD at Durham University, UK, where she focussed on stress, life history and dental development in primates. During her previous postdoctoral work in Cyprus, she was highly involved in non-destructive approaches to the analysis of archaeological human remains, including application of Synchrotron Radiation enabled research in the context of pathology, stress and health in past populations. Within the Dunn Lab, she will contribute to the ALSPAC and STRONG studies working with deciduous teeth to assess the impact of early life adversity and stress on mental health and depression in later life.

  • Mona Le Luyer

    Dr. Mona Le Luyer is a biological anthropologist joining the Dunn Lab as a research fellow. She has extensive experience studying prehistoric and recent human teeth to characterize interactions between biological, environmental, and sociocultural changes. Within the Dunn Lab, she will contribute to the STRONG study using children’s teeth to assess the impact of early life experiences. Mona received her PhD from the University of Bordeaux, France, where she studied dental evolution in Late Pleistocene and Early Holocene human populations. During her postdocs at the University of Kent, UK, she investigated enamel biorhythms and childhood growth trajectories to unlock evidence for understanding the mechanisms underlying dental evolution. She is broadly interested in anything we can learn about teeth and from teeth: identifying any factors or stress that might have impacted dental structures, how and when they got embedded in teeth, understanding their evolution through time and throughout lifespan.

  • Brooke McKenna

    Brooke McKenna, Ph.D., is a clinical psychologist joining the Dunn Lab as a postdoctoral research fellow. She received her doctorate from Emory University in 2023, where she examined the interplay between biological factors (e.g., epi/genetics, gut microbiome) and environmental influences (e.g., childhood trauma, chronic stress) that contribute to psychopathology within and across generations. In the Dunn Lab, Brooke studies how alterations to DNA methylation can help us better understand how adversity and protective factors become biologically embedded to influence the development of psychopathology. Broadly, Brooke's interests center on diversifying science and promoting health equity while examining the biological, social, and developmental factors that contribute to risk and resilience against depression, PTSD, and other psychological disorders.

Data Analysts

  • Anna K. Ruehlmann

    Anna K. Ruehlmann, PhD is a molecular epidemiologist and joins The Dunn Lab as a Senior Data Analyst. She was most recently a post-doctoral fellow at the University of Cincinnati College of Medicine where her research focused on epigenetics and stress, particularly in maternal stress associated with DNA methylation in newborns. She has a diverse scientific background and has contributed to published work in drug development, microbiology, and molecular biology. In the Dunn Lab, Anna hopes to study how ethnic and cultural differences play a role in stress and epigenetic modifications, as well as whether DNA methylation can function as a biomarker for neurodevelopmental disorders early in life.

  • Sammy Stoll

    Sammy joins the Dunn Lab as a Data Analyst. She graduated from the University of Iowa in 2019 with a B.S. in Psychology and minors in Criminology and Human Relations. Sammy has worked as a Research Assistant for the Developmental Psychopathology Lab at Iowa, a Clinical Research Coordinator for the Laboratory for Youth Behavior at MGH, and a Clinical Research Coordinator II here in the Dunn Lab. Her research career has broadly focused on child development, resilience, and behavioral disorder treatment. Sammy is now completing her Master’s in Data Science at DePaul with a concentration in Healthcare. She hopes to continue her work and is looking forward to better understanding what factors may influence vulnerability and resilience towards mental illness.


Clinical Research Coordinators

  • Sherief Eldeeb

    Sherief joins the Dunn Lab as a Senior Clinical Research Coordinator. He graduated from Clark University in 2018 with a B.A. in Psychology (with Highest Honors) and a minor in Biology. As an undergraduate, Sherief worked in a breadth of research areas ranging from neurodevelopmental disorders, trauma in international groups, and addressing mental health disparities. Prior to joining the Dunn Lab, Sherief worked as a Clinical Research Coordinator at the AJ Drexel Autism Institute, where he studied early detection and intervention of autism and Down syndrome. Broadly, his interests include bringing a precision medicine approach to psychopathology with a particular focus on culture. In the Dunn Lab, Sherief is looking forward to better understanding how type and timing of adversities affect different vulnerable groups.

  • Shayari Peiris

    Shayari Peiris is a Clinical Research Coordinator II for the Dunn Lab. She graduated summa cum laude with honors from Wake Forest University in 2021, earning B.A. degrees in psychology and philosophy. From 2021 and 2023, she completed her master's degree in child study and human development at Tufts University, where she received full funding. Shayari previously worked as a clinical research assistant at Boston Children’s Hospital and as a graduate research assistant at the Institute for Applied Research in Youth Development (IARYD). Her research interests include the impact of early life stress on developmental psychopathology, and the multifaceted biological and contextual factors that impact young people’s trajectories of susceptibility and resilience to adverse mental health outcomes. Shayari is enthused to be a member of the Dunn Lab and contribute to uncovering causal mechanisms related to depression risk while aiding in the translation of research discoveries into preventative strategies. Her long-term goal is to pursue a doctoral degree in clinical psychology.

Visiting Graduate Students

  • Anna Großbach

    Anna Großbach joins the Dunn Lab as a visiting PhD student in Genomics Data Science. She graduated from the Johannes Gutenberg University Mainz, Germany, with a B.Sc. in Biology focusing on Molecular Genetics and Genome Evolution. From 2019 to 2021, Anna completed her M.Sc. in Anthropology, with a particular focus on Evolutionary Biology and Bioinformatics. In 2021, she started her PhD in the Simpkin Lab at the University of Galway, Ireland, trying to better understand the dynamics of epigenetics in early stages of life and its susceptibility to external factors, such as adversities.


Undergraduate Students

  • Celia Friedman

    Celia is a fifth-year undergraduate student at Northeastern University studying Economics, Mathematics, and Global Health. She is joining the Dunn lab as a co-op research assistant, where she is excited to learn about biomarkers in mental health. Her research interests are in the intersection of data analysis and biological and psychological data. She hopes to one day pursue epidemiology and early disease detection.


Lab Alumni